"Evening primrose oil supplementation during isotretinoin treatment increased skin hydration, but did not significantly affect transepidermal water loss, skin oiliness, weight loss, or BMI."
Kaźmierska, A., Bolesławska, I., Polańska, A., Dańczak‑Pazdrowska, A., Jagielski, P., Drzymała-Czyż, S., Adamski, Z., & Przysławski, J. (2022). Effect of Evening Primrose Oil Supplementation on Selected Parameters of Skin Condition in a Group of Patients Treated with Isotretinoin—A Randomized Double-Blind Trial. Nutrients, 14. https://doi.org/10.3390/nu14142980.
"Evening primrose oil supplementation improves lipid profiles and reduces transaminase activity in acne patients treated with isotretinoin, but does not affect dietary energy or ingredient content."
Kaźmierska, A., Bolesławska, I., Jagielski, P., Polańska, A., Dańczak‑Pazdrowska, A., Kosewski, G., Adamski, Z., & Przysławski, J. (2022). Effect of Evening Primrose Oil Supplementation on Biochemical Parameters and Nutrition of Patients Treated with Isotretinoin for Acne Vulgaris: A Randomized Double-Blind Trial. Nutrients, 14. https://doi.org/10.3390/nu14071342.
"Evening primrose oil may improve xerotic cheilitis in acne patients treated with oral isotretinoin, but more research is needed for a complete understanding of its role."
Park, K., Ko, E., Kim, I., Li, K., Kim, B., Seo, S., Kim, M., & Hong, C. (2014). The Effect of Evening Primrose Oil for the Prevention of Xerotic Cheilitis in Acne Patients Being Treated with Isotretinoin: A Pilot Study. Annals of Dermatology, 26, 706 - 712. https://doi.org/10.5021/ad.2014.26.6.706.
